产品货号:
Z38212
中文名称:
HLA-DRA抗体
英文名称:
Anti-HLA-DRA Antibody
产品规格:
50μl|100μl|150μl
发货周期:
1~3天
产品价格:
询价
抗体名称 | Anti-HLA-DRA Antibody |
指标别名 | HLA DRA;HLA DRA1;HLA-DR;HLA-DRA;MHC class II antigen DRA |
克隆性 | Monoclonal |
检验物种 | human |
应用范围 | WB,IHC,ICC/IF,FCM |
基因名称 | HLA-DRA |
抗体来源 | Rabbit |
抗体类型 | IgG |
免疫原 | A synthesized peptide derived from human HLA-DRA |
实际分子量 | 35~37KD |
成分 | 500μg/mL;Rabbit IgG in phosphate buffered saline,pH7.4,150mM NaCl,0.02% sodium azide and 50% glycerol. |
纯化方式 | Affinity-chromatography |
浓度 | 500μg/mL |
产品形态 | 溶液 |
保存条件 | 12 months from date of receipt,-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
背景资料 | HLA class II histocompatibility antigen,DR alpha chain is a protein that in humans is encoded by the HLA-DRA gene.It is mapped to 6p21.32.HLA-DRA is one of the HLA class II alpha chain paralogues.This class II molecule is a heterodimer consisting of an alpha and a beta chain,both anchored in the membrane.It plays a central role in the immune system by presenting peptides derived from extracellular proteins.Class II molecules are expressed in antigen presenting cells (APC:B lymphocytes,dendritic cells,macrophages).The alpha chain is approximately 33~35kDa and its gene contains 5 exons.Exon 1 encodes the leader peptide,exons 2 and 3 encode the two extracellular domains,and exon 4 encodes the transmembrane domain and the cytoplasmic tail.DRA does not have polymorphisms in the peptide binding part and acts as the sole alpha chain for DRB1,DRB3,DRB4 and DRB5. |
Uniprot ID | P01903 |
基因名全称 | HLA class II histocompatibility antigen,DR alpha chain |
推荐稀释比 | Western blot (WB) 1:500~2000 Immunohistochemistry in paraffin section (IHC) 1:20~100 Immunocytochemistry/Immunofluorescence(ICC/IF) 1:20~100 Flow cytometry (FCM) 1:20 |
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